Risk Factors For Methamphetamine Use In Youth
Country of origin: USA
Click for Full Details: www.biomedcentral.comMethamphetamine (MA) is a potent stimulant that is readily available. Its effects are similar to cocaine, but the drug has a profile associated with increased acute and chronic toxicities. The objective of a recently published systematic review was to identify and synthesise literature on risk factors that are associated with MA use among youth.
More than 40 electronic databases, websites, and key journals/meeting abstracts were searched. Studies that compared children and adolescents (less than or equal to 18 years) who used MA to those who did not were included.
One reviewer extracted the data and a second checked for completeness and accuracy. For discrete risk factors, odds ratios (OR) were calculated and when appropriate, a pooled OR with 95% confidence intervals (95% CI) was calculated. For continuous risk factors, mean difference and 95% CI were calculated and when appropriate, a weighted mean difference (WMD) and 95% CI were calculated. Results were presented separately by comparison group: low-risk (no previous drug abuse) and high-risk children (reported previous drug abuse or were recruited from a juvenile detention centre).
Twelve studies were included. Among low-risk youth, factors associated with MA use were: history of heroin/opiate use, family history of drug use, risky sexual behaviour and some psychiatric disorders. History of alcohol use and smoking were also significantly associated with MA use. Among high-risk youth, factors associated with MA use were: family history of crime, family history of drug use, family history of alcohol abuse, and psychiatric treatment. Female sex was also significantly associated with MA use.
The research concludes that among low-risk youth, a history of engaging in a variety of risky behaviours was significantly associated with MA use. A history of a psychiatric disorder was a risk factor for MA for both low- and high-risk youth. Family environment was also associated with MA use. Many of the included studies were cross-sectional making it difficult to assess causation. Future research should utilise prospective study designs so that temporal relationships between risk factors and MA use can be established.
The complete article is available as a PDF.
Click for Full Details: www.biomedcentral.com
Calculate by QxMD March 2018
Read by QxMD March 2018
Searching for genetic diversity March 2018
Online medical research March 2018
Better access to medicine safety data March 2018
Free access to databases March 2018
Broncho+ App February 2018
CaseClinic for medical case discussion. February 2018
Comparative toxicogenomics database February 2018
Orlive Surgical Broadcasts February 2018